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Opana ER (extended-release) is a prescription medication that contains the active ingredient oxymorphone, which is a powerful opioid painkiller. It is used to manage moderate to severe pain that requires continuous around-the-clock treatment.

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Like other opioids, Opana ER works by binding to opioid receptors in the brain and spinal cord to reduce the perception of pain. It is designed to provide a steady release of the medication over a 12-hour period.

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